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Accuray Inc, Sunnyvale, CA

Imaging Scientist, Aug 2006 - now

CyberKnife Robotically Assisted Radiosurgery System
Work as an imaging scientist for algorithm research, clinical data evaluation and product development for CyberKnife system.
Enhanced ...... tracking system.
Improve ...... tracking system.
Build batch script environment for clinical data evaluation. The system has been used to test more than ...... image cases.
Develop a high-quality and real-time DRR engine for patient alignment and tumor tracking.
Develop and release the Dynamic Offset Image Calibration feature for CyberKnife imaging system.
Develop and release the Synchrony Trigger X-ray Firing feature for Syncrhony Auto Modeling system.
Actively involved in patent and disclosure activities.
Actively invovled in all R&D, I&T, product release phases.

ISIS Center, Georgetown University, Washington DC

Postdoctoral Research Fellow, December 2003 - Aug 2006

Navigator: prototype surgical navigation system based on AURORA electromagnetic tracking device.
Research work between ISIS Center, Georgetown Hospital, NIH Clinical Center and TRAXTAL company.
System architecture design and development, segmentation and various registration algorithm research, integrating CT and tracked freehand ultrasound image techniques. The system has been used for several swine studies, including liver biopsy, guide-wire tracking, stent deployment, TIPS and radiofrequency ablation. MFC, Open Inventor (Coin3D), ITK, and VTK are used for system design. The software was tested and evaluated in many clinical experiments conducted at Georgetown University Hospital and received good results.
Ultrasound integration in the image guided system.
Research work between ISIS Center, Georgetown Hospital.
Solve the problems in integrating novel ultrasound techniques into current surgical navigation system, including ultrasound calibration, image interpolation, and some deformable motion tracking.
Image guided radiofrequency ablation system.
Research work between Brigham and Women's Hospital, ISIS Center.
Develop and validate an image guided system based on open source software for improved visualization and probe placement during the radiofrequency ablation (RFA) of liver tumors. The whole project include developing an architecture/workstation, semi-automatic segmentation, treatment planning and tracking integration. I am working on the treatment planning and segmentation part. The open source software is based on Slicer and IGSTK.
IGSTK (Image Guided Surgery Toolkit): a general purpose open source package for the image guided system.
Research and development work between Georgetown University, Kitware, Atamai and UNC.
Calibration and Socket Communication component design. The package is based on the ITK / VTK and FLTK, which is trying to encapsulate the segmentation and registration functions of ITK, visualization function of VTK, and some other necessary utilities such as Tracker from Atamai, spatial object hierarchy from UNC and calibration into different plug and play components, open source and platform-independent. The calibration part includes PivotCalibration, PrincipalAxisCalibration, LandmarkUltrasoundCalibration, ReferencePointCalibration and DistortionCalibration.
Deck of cards robot assisted biopsy application.
Research work between ISIS Center.
Develop a robot assisted system for biopsy experiment. The pre-operative image is used for guidance and validation. The robot system in Server/Client mode is controlled by the software through socket and serial communications. The image information is used to plan the path and guide the procedure. I am partly involved in system requirement/architecture design, robot communication.
DirectView software: real-time volume rendering with GPU technique.
Research work for my personal CG interest.
The system is built on DirectX 9, HLSL and Pixel Shader techniques. Displaced pixel shading, early Z-culling, multi-pass rendering are introduced. An intuitive transfer function and shder composer are provided for custom rendering. The software also support script language based on HLSL.

Lab. of Image Science and Technology, Southeast University, Nanjing, China

Research Assistant, September 1998 – July 2003

Virtual medical surgical simulation and analysis program: image processing, visualization and mesh processing.
Research work FOR my PHD thesis.
Ph.D. thesis work, including 3D reconstruction, rendering pipeline framework, mesh decimation and processing, deformable simulation.
DirectView software: real time medical volume rendering.
Research work for part of my PHD thesis.
DirectX 9 with volume texture mapping. A hardware accelerated volume rendering software. Shaders are used for multiple purpose rendering modes.
Interactive virtual endoscopy system.
Advanced China-France Research Project (PRAM 98-01).
Work of M.S. thesis, accelerated ray casting and marching cubes algorithms for rendering, active navigation based on scene analysis. The performance is real-time for internal navigation. An intuitive interface is also provided. Excellent thesis of the University.
Stereo radiological and gamma-knife treatment planning system: volume and surface rendering algorithm.
RESEARCH work for the commercial product of OUR company
Volume and surface rendering modules are designed for gamma-knife treatment planning system. Accelerated ray tracing algorithm is used for volume rendering.
CT blood perfusion system: algorithm design and analysis.
RESEARCH work between Imagetech and ZHONGDA HOSPITAL
A CT perfusion system to analyze the blood flow. CT image slices are analyzed by the time. The blood flow is detected and measured by intensity fitting. The useful information is provided for diagnosis.

East Image Equipments Co., Ltd, Nanjing, China

Senior Researcher and Developer, Part-Time, January 2001 – April 2002

3D visualization and analysis workstation of PACS system.
RESEARCH and development work between IMAGEtech and East Image company.
Based on software design pattern and design procedure, a three layer system architecture is proposed and applied. The top layer is the application level. The intermediate layer is the function widget level. The bottom layer is the package and SDK interface modules. The whole software includes 2D image toolbox display, 2D image analysis and measurement, 3D volume and surface rendering, 3D measurement, virtual endoscopy and navigation system, and also report part. The system can directly access the DICOM images or connect to a PACS system by COM interface. I am the only and core researcher and developer for this system. Detailed techniques used include volume and surface rendering, Open GL / Open Inventor / DirectX 7, Papyrus / CTN for DICOM. MFC is used for GUI. Base on the layer-based system architecture, the system has two different interfaces for differnt purposes.
DICOM server / client.
RESEARCH and development work between IMAGErech and East Image company.
Based on CTN package to transfer the medical images from DICOM3 interface. This is a lite-level server and client used to push and receive medical images through standard DICOM interface.

Lab. of Treatment of Signal and Image, University of Rennes I, Rennes, France

Visiting Scholar, September 2000 – December 2000

Registration of intra-operative X-ray image with pre-operative CT image.
Advanced China-France Research Project (PRAM 98-01).
2D-3D projection registration algorithm using Powel optimization. 2D intra-operative angio images are registered with 3D vessels generated by active navigation during the treatment. The 3D location is easily navigated and located from 2D project. Virtual images, such as virtual endoscopy images, are rendered for surgical navigation.